Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.45 |
| ▸ | HINT1 | P49773 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 2/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.37 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MGMT | P16455 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16690098 | 1.00 | NT5E (0.45) | NT5EHINT1SLC29A1ADORA2AADORA2B | |
| SCHEMBL16689916 | 1.00 | NT5E (0.45) | NT5EHINT1SLC29A1ADORA2AADORA2B | |
| SCHEMBL16690090 | 0.92 | NT5E (0.44) | NT5EHINT1SLC29A1ADORA2AADORA2B | |
| SCHEMBL16689915 | 0.92 | NT5E (0.44) | NT5EHINT1SLC29A1ADORA2AADORA2B | |
| SCHEMBL16690105 | 0.92 | NT5E (0.44) | NT5EHINT1SLC29A1ADORA2AADORA2B | |
| SCHEMBL16690094 | 0.92 | NT5E (0.44) | NT5EHINT1SLC29A1ADORA2AADORA2B | |
| SCHEMBL23010848 | 0.86 | NT5E (0.46) | NT5EHINT1SLC29A1ADORA2AADORA2B | |
| SCHEMBL16689909 | 0.85 | NT5E (0.41) | NT5EHINT1ADORA2AADORA2B | |
| SCHEMBL16188785 | 0.84 | TYMP (0.51) | NT5EADORA1 | |
| SCHEMBL15187543 | 0.83 | ADORA2A (0.52) | NT5ESLC29A1ADORA2AADORA2BADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066370-A1 | D-ALANINE PHOSPHORAMIDATE PRONUCLEOTIDES OF 2'-METHYL 2'-FLUORO GUANOSINE NUCLEOSIDE COMPOUNDS FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |