Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.33 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.33 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HINT1 | P49773 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16689916 | 0.85 | NT5E (0.45) | NT5EADORA2AADORA2BHINT1 | |
| SCHEMBL16690095 | 0.85 | NT5E (0.45) | NT5EADORA2AADORA2BHINT1 | |
| SCHEMBL16690098 | 0.85 | NT5E (0.45) | NT5EADORA2AADORA2BHINT1 | |
| SCHEMBL16690090 | 0.84 | NT5E (0.44) | NT5EADORA2AADORA2BHINT1 | |
| SCHEMBL16690094 | 0.84 | NT5E (0.44) | NT5EADORA2AADORA2BHINT1 | |
| SCHEMBL16689915 | 0.84 | NT5E (0.44) | NT5EADORA2AADORA2BHINT1 | |
| SCHEMBL16690105 | 0.84 | NT5E (0.44) | NT5EADORA2AADORA2BHINT1 | |
| SCHEMBL16689919 | 0.80 | HINT1 (0.48) | NT5EHINT1 | |
| SCHEMBL16690082 | 0.80 | HINT1 (0.48) | NT5EHINT1 | |
| SCHEMBL18089876 | 0.78 | CYP3A4 (0.64) | NT5ECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066370-A1 | D-ALANINE PHOSPHORAMIDATE PRONUCLEOTIDES OF 2'-METHYL 2'-FLUORO GUANOSINE NUCLEOSIDE COMPOUNDS FOR THE TREATMENT OF HCV | IDENIX PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |