Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MGLL | Q99685 | 1/20 | 0.44 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 2/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.42 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18044447 | 0.80 | ATM (0.55) | HPGDNPC1RAB9AKMT2ALMNA | |
| SCHEMBL6261633 | 0.75 | CYP4A11 (0.60) | CYP4A11HPGDMGLLCYP4F2NPC1 | |
| SCHEMBL16334096 | 0.73 | AKT1 (0.49) | HPGDNPC1RAB9AKMT2ALMNA | |
| SCHEMBL16690694 | 0.73 | TDP1 (0.47) | HPGDNPC1RAB9AKMT2ALMNA | |
| SCHEMBL5061105 | 0.73 | MAPT (0.45) | CYP4A11NPC1RAB9AKMT2ALMNA | |
| SCHEMBL2404460 | 0.73 | CYP4A11 (0.73) | CYP4A11MGLLCYP4F2NPC1RAB9A | |
| SCHEMBL4630496 | 0.72 | EGFR (0.45) | NPC1RAB9AKMT2ALMNACA1 | |
| SCHEMBL8322717 | 0.71 | PTGER1 (0.77) | CYP4A11HPGDMGLLCYP4F2RAB9A | |
| SCHEMBL1928912 | 0.71 | TSHR (0.67) | CYP4A11HPGDMGLLCYP4F2NPC1 | |
| SCHEMBL18010709 | 0.71 | PDE4D (0.48) | HPGDRAB9AKMT2ALMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015062555-A1 | COMPOUND HAVING HIGHER INHIBITION OF PROTEIN KINASE G ACTIVITY AND PREPARATION METHOD THEREFOR | 天津键凯科技有限公司 | 2015-05-07 | — | — | WO | disclosed |