Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TPSAB1 | Q15661 | 13/20 | 0.53 |
| ▸ | TPSD1 | Q9BZJ3 | 7/20 | 0.53 |
| ▸ | TPSG1 | Q9NRR2 | 7/20 | 0.53 |
| ▸ | PRSS1 | P07477 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PPID | Q08752 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1668474 | 0.84 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1PRSS1MEN1 | |
| SCHEMBL1669145 | 0.83 | TPSAB1 (0.49) | TPSAB1TPSD1TPSG1PRSS1MEN1 | |
| SCHEMBL1668497 | 0.80 | TPSAB1 (0.53) | TPSAB1TPSD1TPSG1PRSS1MEN1 | |
| Hydrochloric Acid SCHEMBL15861910 | 0.79 | TPSAB1 (0.52) | TPSAB1TPSD1TPSG1PRSS1MEN1 | |
| SCHEMBL1668863 | 0.77 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1PRSS1MEN1 | |
| SCHEMBL1668819 | 0.76 | TPSAB1 (0.49) | TPSAB1TPSD1TPSG1PRSS1MEN1 | |
| SCHEMBL1668562 | 0.75 | TPSAB1 (0.58) | TPSAB1TPSD1TPSG1PRSS1KDM4E | |
| SCHEMBL1668904 | 0.73 | KMT2A (0.57) | TPSAB1TPSD1TPSG1PRSS1MEN1 | |
| Hydrochloric Acid SCHEMBL6784425 | 0.73 | TPSAB1 (0.51) | TPSAB1TPSD1TPSG1PRSS1MEN1 | |
| SCHEMBL12466576 | 0.72 | KDM4E (0.65) | TPSAB1TPSD1TPSG1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011043817-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2011-04-14 | — | — | WO | claimed |