⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14947574 | 0.91 | — | — | |
| SCHEMBL14947601 | 0.79 | — | — | |
| SCHEMBL23645789 | 0.73 | — | — | |
| SCHEMBL19730167 | 0.73 | — | — | |
| SCHEMBL19730166 | 0.73 | — | — | |
| SCHEMBL20326654 | 0.73 | — | — | |
| SCHEMBL6554619 | 0.72 | — | — | |
| SCHEMBL18025439 | 0.72 | — | — | |
| SCHEMBL6555519 | 0.72 | — | — | |
| SCHEMBL1005236 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12071411-B2 | Inhibitors of HIF-2α and methods of use thereof | ARCUS BIOSCIENCES, INC. (US) | 2024-08-27 | — | — | US | disclosed |
| WO-2023210623-A1 | HALOALKYL SULFONE ANILIDE COMPOUND AND HERBICIDE CONTAINING SAME | 株式会社エス・ディー・エス バイオテック | 2023-11-02 | — | — | WO | disclosed |
| US-20230159466-A1 | INHIBITORS OF HIF-2ALPHA AND METHODS OF USE THEREOF | ARCUS BIOSCIENCES, INC. | 2023-05-25 | — | — | US | disclosed |
| CN-112074521-B | Compounds as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | 深圳信立泰药业股份有限公司 | 2022-08-09 | — | — | CN | disclosed |
| CN-112074521-A | Compounds as protease activated receptor 4(PAR4) inhibitors for the treatment of platelet aggregation | 深圳信立泰药业股份有限公司 | 2020-12-11 | — | — | CN | disclosed |
| EP-2611802-B1 | BICYCLIC AZA-HETEROCYCLES AND THEIR USE | BAYER IP GMBH (DE) | 2016-02-24 | — | — | EP | disclosed |
| CN-105294702-A | Fused pyrrolocarbazoles and methods for the preparation thereof | CEPHALON INC | 2016-02-03 | — | — | CN | disclosed |
| US-9096592-B2 | Bicyclic aza heterocycles, and use thereof | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2015-08-04 | — | — | US | disclosed |
| CN-104788459-A | Fused pyrrolocarbazoles and methods for preparation thereof | CEPHALON INC | 2015-07-22 | — | — | CN | disclosed |
| WO-2014184070-A1 | MIXTURES OF HALOALKYLSULFONANILIDE DERIVATIVES AND HERBICIDES | SYNGENTA LIMITED (GB) | 2014-11-20 | — | — | WO | disclosed |
| WO-2007006091-A1 | POLYNUCLEOTIDE MARKER GENES AND THEIR EXPRESSION, FOR DIAGNOSIS OF ENDOTOXEMIA | ATHLOMICS PTY LTD (AU) | 2007-01-18 | — | — | WO | disclosed |
| EP-1711499-A2 | FUSED PYRROLOCARBAZOLES AND METHODS FOR THE PREPARATION THEREOF | CEPHALON, INC. (US) | 2006-10-18 | — | — | EP | disclosed |
| US-7022707-B2 | Piperazine derivatives | HOFFMAN-LA ROCHE INC. (US) | 2006-04-04 | — | — | US | disclosed |
| WO-2005063764-A2 | FUSED PYRROLOCARBAZOLES AND METHODS FOR THE PREPARATION THEREOF | CEPHALON, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| US-20050137245-A1 | Novel fused pyrrolocarbazoles | CEPHALON, INC. | 2005-06-23 | — | — | US | disclosed |
| US-20040235859-A1 | Novel piperazine derivatives | ADAMS DAVID REGINALD (GB) | 2004-11-25 | — | — | US | disclosed |
| EP-1343775-A2 | PIPERAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-09-17 | — | — | EP | disclosed |
| US-20020143020-A1 | Novel piperazine derivatives | VERNALIS RESEARCH LIMITED (GB) | 2002-10-03 | — | — | US | disclosed |
| WO-2002048124-A2 | PIPERAZINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-06-20 | — | — | WO | disclosed |
| US-4511566-A | ANALGESICS | PIERRE FABRE S.A. (FR) | 1985-04-16 | — | — | US | disclosed |