Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | AHR | P35869 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NMT2 | O60551 | 1/20 | 0.47 |
| ▸ | NMT1 | P30419 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9955893 | 0.86 | MAOB (0.60) | MAOBKDM4EAHRAKR1B1ALOX5 | |
| SCHEMBL3460446 | 0.85 | MAOB (0.56) | MAOBKDM4EAHRAKR1B1ALDH1A1 | |
| SCHEMBL8150841 | 0.84 | KDM4E (0.56) | MAOBKDM4EAHRAKR1B1ALDH1A1 | |
| SCHEMBL20558990 | 0.84 | KDM4E (0.48) | MAOBKDM4EALDH1A1KMT2AATM | |
| SCHEMBL22499263 | 0.83 | AKR1B1 (0.55) | MAOBKDM4EAKR1B1ALDH1A1KMT2A | |
| SCHEMBL28368214 | 0.83 | MAOB (0.53) | MAOBKDM4EAHRAKR1B1ALDH1A1 | |
| SCHEMBL31353116 | 0.83 | MAOB (0.53) | MAOBKDM4EAHRAKR1B1ALDH1A1 | |
| SCHEMBL8440469 | 0.83 | MAOB (0.53) | MAOBKDM4EAHRAKR1B1ALOX5 | |
| SCHEMBL15714389 | 0.82 | KDM4E (0.56) | MAOBKDM4EAHRAKR1B1ALDH1A1 | |
| SCHEMBL10395657 | 0.82 | MAOB (0.50) | MAOBKDM4EAHRAKR1B1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015066371-A1 | SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS | FORUM PHARMACEUTICALS, INC. (US) | 2015-05-07 | — | — | WO | disclosed |