SCHEMBL22499263

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL116712	0.85	NPC1 (0.60)	AKR1B1MAPK1MAOBTSHRSLC2A1
	SCHEMBL4251548	0.85	AKR1B1 (0.56)	AKR1B1MAPK1MAOBKMT2AKDM4E
	SCHEMBL21218235	0.84	AKR1B1 (0.55)	AKR1B1MAPK1MAOBKMT2AKDM4E
	SCHEMBL16693136	0.83	MAOB (0.53)	AKR1B1MAOBKMT2AKDM4EALDH1A1
	SCHEMBL30224991	0.83	MAOB (0.56)	AKR1B1MAPK1MAOBKMT2AKDM4E
	SCHEMBL10464658	0.83	MAPK1 (0.57)	AKR1B1MAPK1MAOBKMT2AKDM4E
	SCHEMBL5279035	0.83	MAOB (0.56)	AKR1B1MAPK1MAOBKMT2AKDM4E
	SCHEMBL26645927	0.81	NMT2 (0.54)	AKR1B1MAPK1MAOBKMT2ASLC2A1
	SCHEMBL19744184	0.80	AKR1B1 (0.54)	AKR1B1MAPK1MAOBKMT2ASLC2A1
	SCHEMBL4247906	0.80	AKR1B1 (0.51)	AKR1B1MAPK1MAOBKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.