SCHEMBL16693178

SCHEMBL16693178

N=Cc1cnc2occc2c1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.35
CYP2A6 P11509 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8687301 0.81 PARP1 (0.39) PIK3CDCYP2A6
SCHEMBL2846891 0.81 CYP2A6 (0.50) PIK3CDCYP2A6
SCHEMBL16693206 0.77 ALDH1A1 (0.40) PIK3CDCYP2A6
SCHEMBL13459979 0.71 PIK3CD (0.37) PIK3CD
SCHEMBL12203988 0.71 CCR1 (0.48) PIK3CDCYP2A6
SCHEMBL618751 0.71 IDO1 (0.39) PIK3CD
SCHEMBL18630207 0.71 PIK3CD (0.43) PIK3CD
SCHEMBL17404502 0.70 PIK3CD (0.35) PIK3CD
SCHEMBL2846208 0.70 RECQL (0.36) PIK3CD
SCHEMBL6639359 0.70 PIK3CD (0.37) PIK3CD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015066371-A1 SPIRO-OXADIAZOLINE COMPOUNDS AS AGONISTS OF α-7-NICOTINIC ACETYLCHOLINE RECEPTORS FORUM PHARMACEUTICALS, INC. (US) 2015-05-07 WO disclosed