SCHEMBL16693256

SCHEMBL16693256

C=C(C)C(=O)OCCNC(=O)c1cccc(NC(=O)OC(C)(C)C)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.50
PRMT5 O14744 1/20 0.50
WDR77 Q9BQA1 1/20 0.50
NPSR1 Q6W5P4 2/20 0.49
LMNA P02545 3/20 0.47
MAPT P10636 2/20 0.47
MEN1 O00255 2/20 0.47
KMT2A Q03164 2/20 0.47
HTT P42858 1/20 0.47
HPGD P15428 2/20 0.46
KAT6A Q92794 1/20 0.46
HDAC6 Q9UBN7 2/20 0.44
HDAC3 O15379 1/20 0.44
HDAC1 Q13547 1/20 0.44
HDAC2 Q92769 1/20 0.44
HDAC8 Q9BY41 1/20 0.44
PAX8 Q06710 1/20 0.44
RAB9A P51151 2/20 0.44
CYP17A1 P05093 1/20 0.44
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16693293 0.87 PKM (0.52) SMN1; SMN2NPSR1LMNAHTTHDAC6
SCHEMBL16693233 0.86 SMN1; SMN2 (0.55) SMN1; SMN2PRMT5WDR77LMNAMAPT
SCHEMBL8016168 0.83 KMT2A (0.53) SMN1; SMN2NPSR1LMNAMAPTMEN1
SCHEMBL13359195 0.79 PRMT5 (0.59) SMN1; SMN2PRMT5WDR77LMNAMAPT
SCHEMBL2353901 0.78 HDAC3 (0.52) SMN1; SMN2PRMT5WDR77LMNAMAPT
SCHEMBL2356250 0.77 HDAC3 (0.56) PRMT5WDR77NPSR1LMNAHPGD
SCHEMBL5337975 0.76 CYP1A2 (0.61) SMN1; SMN2NPSR1LMNAMEN1KMT2A
SCHEMBL29867230 0.76 CYP1A2 (0.61) SMN1; SMN2NPSR1LMNAMEN1KMT2A
SCHEMBL14802649 0.75 NPC1 (0.53) SMN1; SMN2LMNAMAPTMEN1KMT2A
SCHEMBL9335874 0.75 PRMT5 (0.51) SMN1; SMN2PRMT5WDR77NPSR1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015064674-A1 METHOD FOR MANUFACTURING POLYMERIZABLE UV-ABSORBING DYE 興和株式会社 2015-05-07 WO disclosed