SCHEMBL166960

SCHEMBL166960

NCCCCCCNS(=O)(=O)c1cccc2c(Cl)cccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 11/20 1.00
CYP1A2 P05177 9/20 1.00
CYP2C19 P33261 9/20 1.00
CYP2C9 P11712 8/20 1.00
TP53 P04637 7/20 1.00
CYP2D6 P10635 6/20 1.00
MEN1 O00255 5/20 1.00
KMT2A Q03164 5/20 1.00
MAPK1 P28482 4/20 1.00
ALDH1A1 P00352 4/20 1.00
TSHR P16473 3/20 1.00
THPO P40225 3/20 1.00
TDP1 Q9NUW8 3/20 1.00
FPR2 P25090 2/20 1.00
MAPT P10636 1/20 1.00
ALOX15 P16050 1/20 1.00
PMP22 Q01453 3/20 0.97
NPSR1 Q6W5P4 3/20 0.97
SCN1A P35498 3/20 0.97
SCN2A Q99250 3/20 0.97

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29695235 1.00 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
SCHEMBL12648358 1.00 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
SCHEMBL9927435 1.00 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
Hydrochloric Acid SCHEMBL30603259 0.99 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
Hydrochloric Acid SCHEMBL30165585 0.99 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
Hydrochloric Acid SCHEMBL897995 0.99 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
Hydrochloric Acid SCHEMBL9895302 0.99 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
Hydrochloric Acid SCHEMBL29734979 0.99 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
SCHEMBL1929636 0.99 CYP3A4 (1.00) CYP3A4CYP1A2CYP2C19CYP2C9TP53
Hydrochloric Acid SCHEMBL15720860 0.97 CYP3A4 (0.95) CYP3A4CYP1A2CYP2C19CYP2C9TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 824 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250160275-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2025-05-22 US claimed
WO-2023164606-A1 COMPOUNDS FOR MODIFYING MEIOTIC RECOMBINATION AND METHODS RELATING THERETO THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (US) 2023-08-31 WO claimed
US-11725227-B2 Devices and methods for examining drug effects on microorganisms ESSENLIX CORPORATION (US) 2023-08-15 US claimed
US-20210369677-A1 SMALL MOLECULE ACTIVATORS OF POLYCYSTIN-2 (PKD2) AND USES THEREOF UNIV NORTHWESTERN (US) 2021-12-02 US claimed
CN-112689758-A Device and method for examining the effect of a drug on microorganisms ESSENLIX公司 2021-04-20 CN claimed
US-20200399675-A1 DEVICES AND METHODS FOR EXAMINING DRUG EFFECTS ON MICROORGANISMS ESSENLIX CORPORATION (US) 2020-12-24 US claimed
WO-2019028133-A1 DEVICES AND METHODS FOR EXAMINING DRUG EFFECTS ON MICROORGANISMS ESSENLIX CORPORATION (US) 2019-02-07 WO claimed
EP-2825173-B1 CALMODULIN INHIBITORS FOR THE TREATMENT OF RIBOSOMAL DISORDERS AND RIBOSOMAPATHIES CHILDRENS MEDICAL CENTER (US) 2018-10-10 EP claimed
US-9976172-B2 Method and apparatus for measuring protein post-translational modification ICAGEN, INC. (US) 2018-05-22 US claimed
WO-2012104788-A2 ANTI-ANGIOGENIC COMPOUNDS, PHARMACEUTICAL COMPOSITIONS CONTAINING SAME, AND USE THEREOF CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) 2012-08-09 WO claimed
EP-0608893-A1 Inhibiting the development of tolerance to and/or dependence on an additive substance VIRGINIA COMMONWEALTH UNIVERSITY (US) 1994-08-03 EP claimed
US-5321012-A Inhibiting the development of tolerance to and/or dependence on a narcotic addictive substance VIRGINIA COMMONWEALTH UNIVERSITY MEDICAL COLLEGE (US) 1994-06-14 US claimed
EP-0428754-B1 HAIR GROWTH STIMULANT SHISEIDO CO LTD (JP) 1994-05-25 EP claimed
EP-0428754-A1 HAIR GROWTH STIMULANT SHISEIDO COMPANY LIMITED (JP) 1991-05-29 EP claimed
EP-0305008-A2 Tumor or cancer cell killing therapy and agents useful therefor OXI-GENE, INC. (US) 1989-03-01 EP claimed
US-4681899-A Method of preventing the growth of malaria parasites in erythrocytes HARTFORD LIFE INSURANCE COMPANY, A CORP. OF CT 1987-07-21 US claimed
US-4476141-A Use of N-(6 aminohexyl)-5-chloro-1-naphthalenesulfonamide, N-(6 aminohexyl)-5-chloro-2-naphthalenesulfonamide, and N-(6 aminohexyl)-5-bromo-2-naphthalenesulfonamide as vaginal contraceptives UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1984-10-09 US claimed
EP-0102162-A1 Use of calmodulin binding drugs for preventing pregnancy THE UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1984-03-07 EP claimed
WO-1984000297-A1 USE OF CALMODULIN BINDING DRUGS AS VAGINAL CONTRACEPTIVES UNIV GEORGIA RES FOUND (US) 1984-02-02 WO claimed
US-4419366-A Use of N-(6 aminohexyl)-5-chloro-1-naphthalenesulfonamide, N-(6 aminohexyl)-5-chloro-2-naphthalenesulfonamide, or N-(6 aminohexyl)-5-bromo-2-naphthalenesulfonamide in the uterus to prevent pregnancy UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) 1983-12-06 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210369677-A1 SMALL MOLECULE ACTIVATORS OF POLYCYSTIN-2 (PKD2) AND USES THEREOF PKD2, PKD1, GLS CYP3A4 4880/4885CYP1A2 4789/4885CYP2C19 4878/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.