Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 6/20 | 0.49 |
| ▸ | CTSB | P07858 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 7/20 | 0.39 |
| ▸ | XPNPEP2 | O43895 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | PEPD | P12955 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19138277 | 0.88 | CAPN1 (0.62) | CAPN1CTSBSLC6A2 | |
| SCHEMBL19138367 | 0.88 | CAPN1 (0.62) | CAPN1CTSBSLC6A2 | |
| SCHEMBL19138299 | 0.88 | CAPN1 (0.62) | CAPN1CTSBSLC6A2 | |
| SCHEMBL19138278 | 0.88 | CAPN1 (0.62) | CAPN1CTSBSLC6A2 | |
| SCHEMBL3778456 | 0.85 | DPP4 (0.49) | ACERENKDM4EF2LMNA | |
| SCHEMBL29860395 | 0.81 | CAPN1 (0.43) | CAPN1CTSBACERENKDM4E | |
| SCHEMBL16695995 | 0.80 | DPP4 (0.56) | CAPN1CTSBACEXPNPEP2REN | |
| SCHEMBL21549057 | 0.80 | DPP4 (0.56) | CAPN1CTSBACEXPNPEP2REN | |
| SCHEMBL26616435 | 0.80 | PREP (0.47) | ACERENKDM4EF2LMNA | |
| SCHEMBL26616445 | 0.80 | PREP (0.47) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065891-A1 | NMDA RECEPTOR MODULATORS AND PRODRUGS, SALTS, AND USES THEREOF | NAUREX, INC. (US) | 2015-05-07 | — | — | WO | disclosed |