Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 2/20 | 0.47 |
| ▸ | FAP | Q12884 | 2/20 | 0.47 |
| ▸ | ACE | P12821 | 9/20 | 0.46 |
| ▸ | REN | P00797 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | LTA4H | P09960 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | PEPD | P12955 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | THPO | P40225 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26616440 | 1.00 | PREP (0.47) | PREPFAPACERENLMNA | |
| SCHEMBL26616445 | 1.00 | PREP (0.47) | PREPFAPACERENLMNA | |
| SCHEMBL23314580 | 0.88 | PREP (0.61) | PREPFAPACERENLMNA | |
| SCHEMBL16021695 | 0.88 | ACE (0.59) | PREPFAPACERENLMNA | |
| SCHEMBL17117574 | 0.87 | PREP (0.46) | PREPFAPACERENLMNA | |
| SCHEMBL13402537 | 0.85 | FAP (0.45) | PREPFAPACERENLMNA | |
| SCHEMBL18681072 | 0.85 | PREP (0.45) | PREPFAPACERENLMNA | |
| SCHEMBL3778456 | 0.85 | DPP4 (0.49) | ACERENLMNAKDM4EF2 | |
| SCHEMBL15727160 | 0.84 | PREP (0.44) | PREPFAPACERENLMNA | |
| SCHEMBL10704033 | 0.84 | REN (0.45) | PREPFAPACERENLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023209191-A1 | PREP BINDING LIGANDS | UNIVERSITY OF HELSINKI (FI) | 2023-11-02 | — | — | WO | disclosed |