Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 3/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.37 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.37 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.37 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.37 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.37 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29606736 | 0.86 | BACE1 (0.48) | NUDT1BACE1 | |
| SCHEMBL15415657 | 0.86 | BACE1 (0.48) | NUDT1BACE1 | |
| Hydrochloric Acid SCHEMBL17074940 | 0.85 | BACE1 (0.47) | NUDT1BACE1 | |
| SCHEMBL16695998 | 0.81 | PLK1 (0.45) | CHEK1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL16696077 | 0.80 | ALDH1A1 (0.45) | CHEK1GABRA1GABRG2GABRB3GABRA5 | |
| SCHEMBL15415545 | 0.79 | KMT2A (0.46) | NUDT1BACE1 | |
| SCHEMBL16696060 | 0.78 | PSEN1 (0.40) | CHEK1PSEN1PSEN2APH1BNCSTN | |
| SCHEMBL16696030 | 0.77 | CYP3A4 (0.45) | — | |
| SCHEMBL15908535 | 0.76 | TBXA2R (0.37) | ALDH1A1LMNA | |
| SCHEMBL15650536 | 0.76 | BACE1 (0.53) | NUDT1BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015065336-A1 | RESPIRATORY SYNCYTIAL VIRUS INHIBITORS | MEDIVIR AB (SE) | 2015-05-07 | — | — | WO | disclosed |