Genipin

Genipin

SCHEMBL16697983

COC(=O)C1=CO[C@@H](O)C2C(CO)=CC[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 9/20 0.70
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
TLR4 O00206 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Genipin SCHEMBL22557817 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL25807077 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL20083921 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL5075862 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL7478142 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL34249 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL9609096 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL13526030 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL5134206 0.99 PTPN1 (0.69) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL19356583 0.97 PTPN1 (0.71) PTPN1MEN1KMT2ATLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250143865-A1 METHODS AND SYSTEMS FOR PREVENTING OR REDUCING STENOSIS IN A SUBJECT RECEIVING A GRAFT MASSACHUSETTS GEN HOSPITAL (US) 2025-05-08 US disclosed
US-12208001-B2 Methods and systems for preventing or reducing stenosis in a subject receiving a graft THE GENERAL HOSPITAL CORPORATION (US) 2025-01-28 US disclosed
US-20220249221-A1 METHODS FOR TISSUE PASSIVATION THE GENERAL HOSPITAL CORPORATION (US) 2022-08-11 US disclosed
US-11337792-B2 Methods for tissue passivation THE GENERAL HOSPITAL CORPORATION (US) 2022-05-24 US disclosed
US-10478284-B2 Methods for tissue passivation THE GENERAL HOSPITAL CORPORATION (US) 2019-11-19 US disclosed
US-20150134049-A1 Methods for Tissue Passivation THE GENERAL HOSPITAL CORPORATION 2015-05-14 US disclosed