Genipin

Genipin

SCHEMBL5075862

COC(=O)C1=CO[C@@H](O)[C@H]2C(CO)=CC[C@H]12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 9/20 0.70
MEN1 O00255 1/20 0.67
KMT2A Q03164 1/20 0.67
TLR4 O00206 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Genipin SCHEMBL22557817 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL25807077 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL16697983 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL20083921 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL7478142 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL34249 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL9609096 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL13526030 1.00 PTPN1 (0.70) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL5134206 0.99 PTPN1 (0.69) PTPN1MEN1KMT2ATLR4
Genipin SCHEMBL19356583 0.97 PTPN1 (0.71) PTPN1MEN1KMT2ATLR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080286329-A1 Methods and Apparatus for Manufacturing Plasma Based Plastics and Bioplastics Produced Therefrom CARNEGIE MELLON UNIVERSITY (US) 2008-11-20 US claimed
US-20080111272-A1 METHOD AND APPARATUS FOR MANUFACTURING PLASMA BASED PLASTICS AND BIOPLASTICS PRODUCED THEREFROM ALLEGHENY-SINGER RESEARCH INSTITUTE 2008-05-15 US claimed
US-20250234857-A1 VESSEL TREATMENT SYSTEMS, METHODS, AND KITS THE GENERAL HOSPITAL CORPORATION 2025-07-24 US disclosed
US-12357547-B2 Compositions containing microcapsules INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2025-07-15 US disclosed
US-12291694-B2 Dye scavenger and method of production of dye scavenger Krusic, Melina Kalagasidis (RS) 2025-05-06 US disclosed
US-12207648-B2 Vessel treatment systems, methods, and kits THE GENERAL HOSPITAL CORPORATION (US) 2025-01-28 US disclosed
EP-3894531-B1 DYE SCAVENGER AND METHOD OF PRODUCTION OF DYE SCAVENGER KALAGASIDIS KRUSIC MELINA (RS) 2024-06-19 EP disclosed
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER HFC PRESTIGE SERVICE GERMINY GMBH (DE) 2023-10-05 US disclosed
US-20230172820-A1 Compositions Containing Microcapsules INTERNATIONAL FLAVORS & FRAGRANCES INC. 2023-06-08 US disclosed
EP-4171500-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER Wella Germany GmbH (DE) 2023-05-03 EP disclosed
CN-115806633-A Genipin-crosslinked PDRN-SACRAN biopolymer scaffold 比贝婷作物科学有限公司 2023-03-17 CN disclosed
US-20220160752-A1 GENIPIN-CROSSLINKED PDRN-SACRAN BIOPOLYMER SCAFFOLDS PERPETUUM CROPSCIENCE BVBA (BE) 2022-05-26 US disclosed
EP-3122444-B1 PROCESS FOR MAKING MEMBRANES APPLIED BIOMIMETIC AS (DK) 2021-06-30 EP disclosed
US-9364503-B2 Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom CARMELL THERAPEUTICS CORPORATION (US) 2016-06-14 US disclosed
US-20150165093-A1 Methods and Apparatus for Manufacturing Plasma Based Plastics and Bioplastics Produced Therefrom ALLEGHENY-SINGER RESEARCH INSTITUTE 2015-06-18 US disclosed
US-8911789-B2 Methods and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom CARNEGIE MELLON UNIVERSITY (US) 2014-12-16 US disclosed
US-20130189370-A1 Methods and Apparatus for Manufacturing Plasma Based Plastics and Bioplastics Produced Therefrom CARNEGIE MELLON UNIVERSITY (US) 2013-07-25 US disclosed
US-20130108671-A1 HEMOSTATIC COMPOSITIONS BAXTER HEALTHCARE S.A. (CH) 2013-05-02 US disclosed
US-8293530-B2 Method and apparatus for manufacturing plasma based plastics and bioplastics produced therefrom CARNEGIE MELLON UNIVERSITY (US) 2012-10-23 US disclosed
US-20080111272-A1 METHOD AND APPARATUS FOR MANUFACTURING PLASMA BASED PLASTICS AND BIOPLASTICS PRODUCED THEREFROM ALLEGHENY-SINGER RESEARCH INSTITUTE 2008-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12357547-B2 Compositions containing microcapsules COPE, SAAL1, AUP1 PTPN1 2015/4885MEN1 2096/4885KMT2A 4219/4885
US-20230310300-A1 HAIR COLOURING COMPOSITIONS COMPRISING A BIO-BASED POLYMER AND A CROSSLINKER KRT18, MKI67, IK PTPN1 1537/4885MEN1 811/4885KMT2A 876/4885
US-20230172820-A1 Compositions Containing Microcapsules COPE, SAAL1, AUP1 PTPN1 2015/4885MEN1 2096/4885KMT2A 4219/4885
US-20220160752-A1 GENIPIN-CROSSLINKED PDRN-SACRAN BIOPOLYMER SCAFFOLDS PARN, GMNN, POLN PTPN1 2724/4885MEN1 4497/4885KMT2A 4107/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.