SCHEMBL16698253

SCHEMBL16698253

Nc1cccc(Nc2nc(Nc3cccc(N)c3)nc(Nc3ccccc3O)n2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 6/20 0.50
MAPT P10636 5/20 0.50
MEN1 O00255 4/20 0.50
KMT2A Q03164 4/20 0.50
LMNA P02545 2/20 0.50
KDM4E B2RXH2 2/20 0.50
GFER P55789 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
POLB P06746 2/20 0.47
XBP1 P17861 1/20 0.47
HTT P42858 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
SYK P43405 1/20 0.47
FCGR3B O75015 1/20 0.46
FCGR1A P12314 1/20 0.46
FCGR2A P12318 1/20 0.46
RHOA P61586 1/20 0.44
ABL1 P00519 2/20 0.44
BCR P11274 2/20 0.44
SRC P12931 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11795454 0.83 MEN1 (0.63) GAAMAPTMEN1KMT2ALMNA
SCHEMBL31302305 0.83 MEN1 (0.63) GAAMAPTMEN1KMT2ALMNA
SCHEMBL16698318 0.83 MAPT (0.49) GAAMAPTMEN1KMT2AKDM4E
SCHEMBL30562985 0.82 MEN1 (0.74) GAAMAPTMEN1KMT2ALMNA
SCHEMBL30433848 0.82 CXCR2 (0.56) GAAMAPTMEN1KMT2ALMNA
SCHEMBL14236870 0.82 MEN1 (0.74) GAAMAPTMEN1KMT2ALMNA
SCHEMBL31149855 0.82 TP53 (0.53) GAAMAPTMEN1KMT2ALMNA
SCHEMBL4568692 0.82 NFKB1 (0.56) GAAMAPTMEN1KMT2ALMNA
SCHEMBL16011075 0.82 TP53 (0.53) GAAMAPTMEN1KMT2ALMNA
SCHEMBL5959497 0.80 GBA1 (0.51) GAAMAPTMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9556312-B2 Polyimide precursor, polyimide, polyimide film, polyimide metal laminate, and polyimide solution NATIONAL UNIVERSITY CORPORATION IWATE UNIVERSITY (JP) 2017-01-31 US disclosed
US-20150132591-A1 POLYIMIDE PRECURSOR, POLYIMIDE, POLYIMIDE FILM, POLYIMIDE METAL LAMINATE, AND POLYIMIDE SOLUTION UBE CORPORATION (JP) 2015-05-14 US disclosed