Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7508636 | 0.91 | MAPK1 (0.56) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL27868016 | 0.91 | MAPK1 (0.56) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL13447325 | 0.88 | MAPK1 (0.58) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL8828727 | 0.85 | MEN1 (0.61) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL15522833 | 0.84 | LMNA (0.54) | MEN1KMT2ASMN1; SMN2ALDH1A1POLB | |
| SCHEMBL15581472 | 0.83 | MEN1 (0.62) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL4519283 | 0.82 | MEN1 (0.64) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL13412481 | 0.80 | SMN1; SMN2 (0.56) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL24387105 | 0.79 | KMT2A (0.61) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 | |
| SCHEMBL13807662 | 0.79 | MEN1 (0.61) | MEN1KMT2AMAPK1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2482815-A1 | ANTI INFLAMMATORY 2-OXOTHIAZOLES AND 2 -OXOOXAZOLES | Avexxin AS (NO) | 2012-08-08 | — | — | EP | disclosed |
| WO-2011039365-A1 | ANTI INFLAMMATORY 2-OXOTHIAZOLES AND 2 -OXOOXAZOLES | AVEXXIN AS (NO) | 2011-04-07 | — | — | WO | disclosed |