Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.67 |
| ▸ | MEN1 | O00255 | 6/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.67 |
| ▸ | GAA | P10253 | 3/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.67 |
| ▸ | NPY1R | P25929 | 1/20 | 0.67 |
| ▸ | NPY2R | P49146 | 1/20 | 0.67 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.67 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.67 |
| ▸ | TP53 | P04637 | 3/20 | 0.65 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16700272 | 0.86 | PIN1 (0.53) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16699070 | 0.86 | MAPT (0.61) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16699136 | 0.82 | SMN1; SMN2 (0.65) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16699399 | 0.80 | MAPT (0.65) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16700001 | 0.79 | TP53 (0.58) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16699017 | 0.78 | MAPT (0.58) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16699079 | 0.77 | MAPT (0.60) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16699456 | 0.77 | POLB (0.58) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL4741860 | 0.77 | MAPT (0.80) | MAPTMEN1KMT2ASMN1; SMN2GAA | |
| SCHEMBL16699081 | 0.77 | MAPT (0.56) | MAPTMEN1KMT2ASMN1; SMN2GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150132342-A1 | NOVEL IMMUNE ACTIVATORS: SUBSTITUTE 4-AMINOQUINAZOLINES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150132342-A1 | NOVEL IMMUNE ACTIVATORS: SUBSTITUTE 4-AMINOQUINAZOLINES | TLR4, TLR7, TLR2 | MAPT 4782/4885MEN1 4779/4885KMT2A 840/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.