Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | KDM1A | O60341 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670617 | 0.85 | — | — | |
| SCHEMBL1670618 | 0.85 | — | — | |
| SCHEMBL1670042 | 0.82 | AR (0.32) | ARHSD11B1 | |
| SCHEMBL1670168 | 0.82 | MGLL (0.36) | MGLLESR1ESR2KDM1AAR | |
| SCHEMBL1671862 | 0.78 | ESR1 (0.36) | ESR1ESR2AR | |
| SCHEMBL1671861 | 0.78 | ESR1 (0.36) | ESR1ESR2AR | |
| SCHEMBL1671153 | 0.76 | MGLL (0.40) | MGLLESR1ESR2KDM1AAR | |
| SCHEMBL1671152 | 0.76 | MGLL (0.40) | MGLLESR1ESR2KDM1AAR | |
| SCHEMBL1670841 | 0.72 | — | — | |
| SCHEMBL1672828 | 0.72 | NPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | disclosed |