Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Nitric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | FGB | P02675 | 1/20 | 0.36 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL372498 | 0.87 | KDM4E (0.44) | KDM4ECYP2D6TSHRL3MBTL1KMT2A | |
| Bromide SCHEMBL28152662 | 0.85 | KDM4E (0.43) | KDM4ECYP2D6TSHRL3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL28772143 | 0.85 | KDM4E (0.43) | KDM4ECYP2D6TSHRL3MBTL1KMT2A | |
| Nitric Acid SCHEMBL16700627 | 0.84 | L3MBTL1 (0.44) | KDM4ECYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL27713110 | 0.83 | KDM4E (0.41) | KDM4ECYP2D6TSHRL3MBTL1KMT2A | |
| Nitric Acid SCHEMBL27774290 | 0.82 | KDM4E (0.46) | KDM4ECYP2D6TSHRCYP2C19HIF1A | |
| SCHEMBL27945657 | 0.82 | KDM4E (0.41) | KDM4ECYP2D6TSHRL3MBTL1KMT2A | |
| Nitric Acid SCHEMBL25234257 | 0.81 | KDM4E (0.41) | KDM4ECYP2D6TSHRCYP2C19HIF1A | |
| Trifluoromethanesulfonic Acid SCHEMBL16699953 | 0.81 | KMT2A (0.42) | KDM4ECYP2D6TSHRL3MBTL1KMT2A | |
| SCHEMBL29278234 | 0.80 | KDM4E (0.40) | KDM4ECYP2D6TSHRL3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3244987-B1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2022-06-22 | — | — | EP | claimed |
| US-10227274-B2 | Separations with ionic liquid solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2019-03-12 | — | — | US | claimed |
| EP-3244987-A1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | Chevron Phillips Chemical Company LP (US) | 2017-11-22 | — | — | EP | claimed |
| US-20150133711-A1 | Separations With Ionic Liquid Solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2015-05-14 | — | — | US | claimed |
| EP-3244987-B1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | CHEVRON PHILLIPS CHEMICAL CO LP (US) | 2022-06-22 | — | — | EP | disclosed |
| US-10227274-B2 | Separations with ionic liquid solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP (US) | 2019-03-12 | — | — | US | disclosed |
| EP-3244987-A1 | SEPARATIONS WITH IONIC LIQUID SOLVENTS | Chevron Phillips Chemical Company LP (US) | 2017-11-22 | — | — | EP | disclosed |
| US-20150133711-A1 | Separations With Ionic Liquid Solvents | CHEVRON PHILLIPS CHEMICAL COMPANY LP | 2015-05-14 | — | — | US | disclosed |