SCHEMBL16701293

SCHEMBL16701293

O=C1c2ccccc2C(=O)N1CC(O)CNc1ccc(F)c(F)c1

nearest known ligand 0.66

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.66
MAPT P10636 1/20 0.66
RAB9A P51151 2/20 0.46
KDM4E B2RXH2 1/20 0.46
HPGD P15428 1/20 0.46
RPS6KA2 Q15349 3/20 0.46
MAPK1 P28482 1/20 0.44
KMT2A Q03164 3/20 0.43
MEN1 O00255 1/20 0.40
GAA P10253 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 1/20 0.39
TSHR P16473 1/20 0.39
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16701290 1.00 ALDH1A1 (0.66) ALDH1A1MAPTRAB9AKDM4EHPGD
SCHEMBL4573543 0.89 ALDH1A1 (0.69) ALDH1A1MAPTRAB9AKDM4EHPGD
SCHEMBL4573547 0.89 ALDH1A1 (0.69) ALDH1A1MAPTRAB9AKDM4EHPGD
SCHEMBL16204409 0.83 MAPT (0.55) ALDH1A1MAPTRAB9AKDM4EHPGD
SCHEMBL16197764 0.81 ALDH1A1 (0.53) ALDH1A1MAPTRAB9AKDM4EHPGD
SCHEMBL3941177 0.81 ALDH1A1 (0.53) ALDH1A1MAPTRAB9AKDM4EHPGD
SCHEMBL29746037 0.81 ALDH1A1 (0.53) ALDH1A1MAPTRAB9AKDM4EHPGD
SCHEMBL10689999 0.81 ALDH1A1 (0.64) ALDH1A1MAPTRAB9AKDM4EHPGD
SCHEMBL13232278 0.80 ALDH1A1 (0.75) ALDH1A1MAPTRAB9AKDM4ERPS6KA2
SCHEMBL18263606 0.80 ALDH1A1 (0.63) ALDH1A1MAPTRAB9ARPS6KA2MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3065740-B1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LTD (IN) 2018-08-22 EP claimed
US-9573910-B2 Oxazolidinone antibacterial compound LEE PHARMA LIMITED (IN) 2017-02-21 US claimed
US-20160272597-A1 Novel Oxazolidinone Antibacterial Compound LEE PHARMA LIMITED (IN) 2016-09-22 US claimed
EP-3065740-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND Lee Pharma Ltd. (IN) 2016-09-14 EP claimed
WO-2015068173-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LIMITED (IN) 2015-05-14 WO claimed
WO-2015068171-A1 NOVEL OXAZOLIDINONE COMPOUNDS LEE PHARMA LIMITED (IN) 2015-05-14 WO claimed
EP-3065740-B1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LTD (IN) 2018-08-22 EP disclosed
US-9573910-B2 Oxazolidinone antibacterial compound LEE PHARMA LIMITED (IN) 2017-02-21 US disclosed
US-20160272597-A1 Novel Oxazolidinone Antibacterial Compound LEE PHARMA LIMITED (IN) 2016-09-22 US disclosed
EP-3065740-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND Lee Pharma Ltd. (IN) 2016-09-14 EP disclosed
WO-2015068173-A1 NOVEL OXAZOLIDINONE ANTIBACTERIAL COMPOUND LEE PHARMA LIMITED (IN) 2015-05-14 WO disclosed
WO-2015068171-A1 NOVEL OXAZOLIDINONE COMPOUNDS LEE PHARMA LIMITED (IN) 2015-05-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160272597-A1 Novel Oxazolidinone Antibacterial Compound OXA1L, ODC1, AZI2 ALDH1A1 2873/4885MAPT 4185/4885RAB9A 3752/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.