⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670167 | 1.00 | — | — | |
| SCHEMBL15260093 | 1.00 | — | — | |
| Bromide SCHEMBL5420538 | 0.97 | — | — | |
| SCHEMBL20326800 | 0.73 | TSHR (0.31) | — | |
| SCHEMBL24934021 | 0.71 | — | — | |
| SCHEMBL19266821 | 0.71 | — | — | |
| Dimethylformamide SCHEMBL28155853 | 0.69 | — | — | |
| SCHEMBL359274 | 0.69 | — | — | |
| SCHEMBL9249509 | 0.67 | — | — | |
| SCHEMBL9249500 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20170260178-A1 | ANTIBACTERIAL COMPOUNDS | SPERO GYRASE INC (US) | 2017-09-14 | — | — | US | disclosed |
| EP-2828257-B1 | ANTIBACTERIAL COMPOUNDS | BIOTA EUROPE LTD (GB) | 2017-07-26 | — | — | EP | disclosed |
| US-9604976-B2 | Antibacterial compounds | SPERO GYRASE, INC. (US) | 2017-03-28 | — | — | US | disclosed |
| US-20150329530-A1 | ANTIBACTERIAL COMPUNDS | SPERO GYRASE, INC. | 2015-11-19 | — | — | US | disclosed |
| US-9056858-B2 | Indazole and pyrazolopyridine compounds as CCR1 receptor antagonists | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2015-06-16 | — | — | US | disclosed |
| EP-2828257-A1 | ANTIBACTERIAL COMPOUNDS | Biota Europe Ltd (GB) | 2015-01-28 | — | — | EP | disclosed |
| US-8906902-B2 | Antibacterial compounds | BIOTA EUROPE LIMITED (GB) | 2014-12-09 | — | — | US | disclosed |
| EP-2178375-B1 | PYRAZOLOÝ1,5-A¨PYRIMIDINE DERIVATIVES | MERCK SHARP & DOHME (US) | 2014-09-24 | — | — | EP | disclosed |
| EP-2491028-B1 | INDAZOLE AND PYRAZOLOPYRIDINE COMPOUNDS AS CCR1 RECEPTOR ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2013-12-11 | — | — | EP | disclosed |
| EP-2178375-A1 | PYRAZOLOÝ1,5-A¨PYRIMIDINE DERIVATIVES | Merck Sharp & Dohme Corp. (US) | 2010-04-28 | — | — | EP | disclosed |
| US-7534799-B2 | Pyridomorphinans, thienomorphinans and use thereof | SOUTHERN RESEARCH INSTITUTE (US) | 2009-05-19 | — | — | US | disclosed |
| WO-2009014620-A1 | PYRAZOLO[1,5-A]PYRIMIDINE DERIVATIVES | MERCK & CO., INC. (US) | 2009-01-29 | — | — | WO | disclosed |
| US-20060264452-A1 | Pyridomorphinans, thienomorphinans and use thereof | SOUTHERN RESEARCH INSTITUTE (US) | 2006-11-23 | — | — | US | disclosed |
| US-7105675-B2 | Pyridomorphinans, thienomorphinans and use thereof | SOUTHERN RESEARCH INSTITUTE (US) | 2006-09-12 | — | — | US | disclosed |
| US-7015326-B1 | Pyridomorphinans, thienomorphinans and use thereof | SOUTHERN RESEARCH INSTITUTE (US) | 2006-03-21 | — | — | US | disclosed |
| US-20060047119-A1 | Pyridomorphinans, thienomorphinans and use thereof | SOUTHERN RESEARCH INSTITUTE (US) | 2006-03-02 | — | — | US | disclosed |
| EP-1210084-A4 | PYRIDOMORPHINANS, THIENOMOPRHINANS AND USE THEREOF | SOUTHERN RES INST (US) | 2002-11-13 | — | — | EP | disclosed |
| EP-1210084-A1 | PYRIDOMORPHINANS, THIENOMOPRHINANS AND USE THEREOF | Southern Research Institute (US) | 2002-06-05 | — | — | EP | disclosed |
| WO-2001012197-A1 | PYRIDOMORPHINANS, THIENOMOPRHINANS AND USE THEREOF | SOUTHERN RESEARCH INSTITUTE (US) | 2001-02-22 | — | — | WO | disclosed |