Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.53 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
| ▸ | F2 | P00734 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16703025 | 1.00 | DPP4 (0.54) | DPP4OPRM1OPRD1DPP8OPRK1 | |
| SCHEMBL30814251 | 1.00 | DPP4 (0.54) | DPP4OPRM1OPRD1DPP8OPRK1 | |
| SCHEMBL16703340 | 1.00 | DPP4 (0.54) | DPP4OPRM1OPRD1DPP8OPRK1 | |
| SCHEMBL20853463 | 1.00 | DPP4 (0.54) | DPP4OPRM1OPRD1DPP8OPRK1 | |
| Hydrochloric Acid SCHEMBL16703248 | 0.99 | DPP4 (0.53) | DPP4OPRM1OPRD1DPP8OPRK1 | |
| Hydrochloric Acid SCHEMBL18094974 | 0.99 | DPP4 (0.53) | DPP4OPRM1OPRD1DPP8OPRK1 | |
| SCHEMBL31230863 | 0.95 | OPRM1 (0.58) | DPP4OPRM1OPRD1F2 | |
| SCHEMBL20853476 | 0.95 | OPRM1 (0.58) | DPP4OPRM1OPRD1F2 | |
| SCHEMBL18094994 | 0.95 | OPRM1 (0.58) | DPP4OPRM1OPRD1F2 | |
| SCHEMBL16702684 | 0.95 | OPRM1 (0.58) | DPP4OPRM1OPRD1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3066091-A1 | NMDA ANTAGONIST PRODRUGS | Astrazeneca AB (SE) | 2016-09-14 | — | — | EP | claimed |
| WO-2015067923-A1 | NMDA ANTAGONIST PRODRUGS | ASTRAZENECA AB (SE) | 2015-05-14 | — | — | WO | claimed |
| WO-2024050389-A1 | COMBINATION THERAPIES INCLUDING METAL CHANNEL ACTIVATORS AND NMDA RECEPTOR ANTAGONISTS | BIOHAVEN THERAPEUTICS LTD. (VG) | 2024-03-07 | — | — | WO | disclosed |