SCHEMBL16704264

SCHEMBL16704264

Nc1ccnnc1C1OCCO1

nearest known ligand 0.40

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
NSD2 O96028 1/20 0.40
CASP6 P55212 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28226721 0.74 USP2 (0.31)
SCHEMBL1991557 0.73 CASP6 (0.50) NSD2CASP6
SCHEMBL8683445 0.63 NSD2 (0.48) NSD2CASP6
SCHEMBL1050861 0.62
SCHEMBL2044973 0.60
Hydrochloric Acid SCHEMBL10675414 0.60
SCHEMBL1992801 0.59 NSD2 (0.44) NSD2CASP6
SCHEMBL5485539 0.58 NSD2 (0.40) NSD2CASP6
SCHEMBL5923888 0.58
SCHEMBL5775157 0.58

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3066093-A1 GSK-3 INHIBITORS Bristol-Myers Squibb Company (US) 2016-09-14 EP disclosed
WO-2015069594-A1 GSK-3 INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2015-05-14 WO disclosed