Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F3 | P13726 | 1/20 | 0.73 |
| ▸ | CES2 | O00748 | 1/20 | 0.73 |
| ▸ | CES1 | P23141 | 1/20 | 0.73 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.65 |
| ▸ | RORC | P51449 | 9/20 | 0.64 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.60 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.60 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.60 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.60 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.59 |
| ▸ | USP2 | O75604 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.59 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.59 |
| ▸ | ALB | P02768 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | GLI1 | P08151 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
| ▸ | NT5E | P21589 | 1/20 | 0.59 |
| ▸ | DPP4 | P27487 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16704985 | 0.93 | F3 (0.62) | F3CES2CES1TRPV1RORC | |
| SCHEMBL4213368 | 0.92 | TRPV1 (0.76) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL15450746 | 0.91 | TRPV1 (0.64) | F3CES2CES1TRPV1RORC | |
| SCHEMBL15450687 | 0.90 | TRPV1 (0.59) | F3CES2CES1TRPV1RORC | |
| SCHEMBL16704668 | 0.89 | TRPV1 (0.59) | F3CES2CES1TRPV1RORC | |
| SCHEMBL16705023 | 0.87 | F3 (0.72) | F3CES2CES1RORCPTPN1 | |
| SCHEMBL12134013 | 0.87 | F3 (0.72) | F3CES2CES1RORCPTPN1 | |
| SCHEMBL16704682 | 0.87 | F3 (0.72) | F3CES2CES1RORCPTPN1 | |
| SCHEMBL16704695 | 0.87 | F3 (0.72) | F3CES2CES1RORCPTPN1 | |
| SCHEMBL16704995 | 0.86 | F3 (0.79) | F3CES2CES1RORCEGLN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029414-B2 | Triterpenoid compounds and methods of use thereof | BIOTECHNOLOGY RESEARCH CORPORATION (HK) | 2015-05-12 | — | — | US | disclosed |
| US-9029414-B2 | Triterpenoid compounds and methods of use thereof | BIOTECHNOLOGY RESEARCH CORPORATION (HK) | 2015-05-12 | — | — | US | disclosed |