Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.76 |
| ▸ | RORC | P51449 | 14/20 | 0.74 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.71 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.71 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.71 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.71 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.71 |
| ▸ | ALB | P02768 | 2/20 | 0.71 |
| ▸ | USP2 | O75604 | 1/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.71 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.71 |
| ▸ | POLB | P06746 | 1/20 | 0.71 |
| ▸ | GLI1 | P08151 | 1/20 | 0.71 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.71 |
| ▸ | NT5E | P21589 | 1/20 | 0.71 |
| ▸ | DPP4 | P27487 | 1/20 | 0.71 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.71 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.71 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451317 | 0.94 | TRPV1 (0.74) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL12557941 | 0.93 | TRPV1 (0.75) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL13628225 | 0.92 | RORC (0.73) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL12557957 | 0.92 | RORC (0.80) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL16704676 | 0.92 | F3 (0.73) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL13628230 | 0.92 | TRPV1 (0.74) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL4442339 | 0.92 | TRPV1 (0.74) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL13637466 | 0.92 | TRPV1 (0.76) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL12557958 | 0.92 | RORC (0.75) | TRPV1RORCEGLN2EGLN1EGLN3 | |
| SCHEMBL13628219 | 0.92 | TRPV1 (0.76) | TRPV1RORCEGLN2EGLN1EGLN3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8623848-B2 | Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods | UNIVERSITY OF OTTAWA (CA) | 2014-01-07 | — | — | US | claimed |
| US-20090143350-A1 | Anxiolytic Marcgraviaceae Compositions Containing Betulinic Acid, Betulinic Acid Derivatives, and Methods | UNIVERSITY OF OTTAWA | 2009-06-04 | — | — | US | claimed |
| US-20040235805-A1 | Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods | PALADIN LABS INC. (CA) | 2004-11-25 | — | — | US | claimed |
| EP-1476031-A1 | ANXIOLYTIC MARCGRAVIACEAE COMPOSITIONS CONTAINING BETULINIC ACID, BETULINIC ACID DERIVATIVES, AND METHODS | University of Ottawa (CA) | 2004-11-17 | — | — | EP | claimed |
| WO-2002091858-A1 | ANXIOLYTIC MARCGRAVIACEAE COMPOSITIONS CONTAINING BETULINIC ACID, BETULINIC ACID DERIVATIVES, AND METHODS | UNIVERSITY OF OTTAWA (CA) | 2002-11-21 | — | — | WO | claimed |
| US-20150005267-A1 | ANXIOLYTIC MARCGRAVIACEAE COMPOSITIONS CONTAINING BETULINIC ACID, BETULINIC ACID DERIVATIVES, AND METHODS | UNIV OTTAWA (CA) | 2015-01-01 | — | — | US | disclosed |
| US-8623848-B2 | Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods | UNIVERSITY OF OTTAWA (CA) | 2014-01-07 | — | — | US | disclosed |
| EP-2567625-A1 | Preparation containing betulinic acid, obtained from a plant of the family Marcgraviaceae | UNIVERSITY OF OTTAWA (CA) | 2013-03-13 | — | — | EP | disclosed |
| US-20110144069-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | MYRIAD GENETICS, INCORPORATED (US) | 2011-06-16 | — | — | US | disclosed |
| US-20110144069-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | MYRIAD GENETICS, INCORPORATED (US) | 2011-06-16 | — | — | US | disclosed |
| US-20090149429-A1 | ANTIVIRAL COMPOUNDS | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-11 | — | — | US | disclosed |
| US-20090149429-A1 | ANTIVIRAL COMPOUNDS | MYRIAD GENETICS, INCORPORATED (US) | 2009-06-11 | — | — | US | disclosed |
| US-20090105203-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | MYRIAD GENETICS, INCORPORATED (US) | 2009-04-23 | — | — | US | disclosed |
| US-20090105203-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | MYRIAD GENETICS, INCORPORATED (US) | 2009-04-23 | — | — | US | disclosed |
| US-7488722-B2 | Anxiolytic Marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods | UNIVERSITY OF OTTAWA (CA) | 2009-02-10 | — | — | US | disclosed |
| US-20080207573-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | MYRIAD GENETICS, INCORPORATED (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207573-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | MYRIAD GENETICS, INCORPORATED (US) | 2008-08-28 | — | — | US | disclosed |
| US-20040235805-A1 | Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods | PALADIN LABS INC. (CA) | 2004-11-25 | — | — | US | disclosed |
| EP-1476031-A1 | ANXIOLYTIC MARCGRAVIACEAE COMPOSITIONS CONTAINING BETULINIC ACID, BETULINIC ACID DERIVATIVES, AND METHODS | University of Ottawa (CA) | 2004-11-17 | — | — | EP | disclosed |
| WO-2002091858-A1 | ANXIOLYTIC MARCGRAVIACEAE COMPOSITIONS CONTAINING BETULINIC ACID, BETULINIC ACID DERIVATIVES, AND METHODS | UNIVERSITY OF OTTAWA (CA) | 2002-11-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090105203-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | HAVCR2, MAVS, CCL11 | TRPV1 372/4885RORC 41/4885EGLN2 332/4885 |
| US-20090149429-A1 | ANTIVIRAL COMPOUNDS | ZC3HAV1, MAVS, EIF2AK2 | TRPV1 3298/4885RORC 965/4885EGLN2 1098/4885 |
| US-20090143350-A1 | Anxiolytic Marcgraviaceae Compositions Containing Betulinic Acid, Betulinic Acid Derivatives, and Methods | GABRA5, GABRA6, GABRA1 | TRPV1 2359/4885RORC 372/4885EGLN2 2147/4885 |
| US-20040235805-A1 | Anxiolytic marcgraviaceae compositions containing betulinic acid, betulinic acid derivatives, and methods | GABRA5, GABRA6, GABRA1 | TRPV1 2359/4885RORC 372/4885EGLN2 2147/4885 |
| US-20080207573-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | HAVCR2, MAVS, CCL11 | TRPV1 372/4885RORC 41/4885EGLN2 332/4885 |
| US-20110144069-A1 | COMPOUNDS FOR TREATING VIRAL INFECTIONS | HAVCR2, MAVS, CCL11 | TRPV1 372/4885RORC 41/4885EGLN2 332/4885 |
| US-20150005267-A1 | ANXIOLYTIC MARCGRAVIACEAE COMPOSITIONS CONTAINING BETULINIC ACID, BETULINIC ACID DERIVATIVES, AND METHODS | GABRA5, GABRA6, GABRA1 | TRPV1 2359/4885RORC 372/4885EGLN2 2147/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.