Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 11/20 | 0.83 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.83 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.83 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.83 |
| ▸ | F3 | P13726 | 4/20 | 0.76 |
| ▸ | USP2 | O75604 | 2/20 | 0.76 |
| ▸ | LMNA | P02545 | 1/20 | 0.76 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.76 |
| ▸ | USP7 | Q93009 | 1/20 | 0.76 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.76 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.76 |
| ▸ | TOP2A | P11388 | 1/20 | 0.66 |
| ▸ | PTPN2 | P17706 | 6/20 | 0.64 |
| ▸ | PTPN6 | P29350 | 2/20 | 0.64 |
| ▸ | EGFR | P00533 | 1/20 | 0.61 |
| ▸ | CES2 | O00748 | 1/20 | 0.61 |
| ▸ | CES1 | P23141 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17332299 | 1.00 | PTPN1 (0.83) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL16704679 | 0.94 | ALOX5 (0.80) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| Erythrodiol SCHEMBL18625203 | 0.91 | PTPN1 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| Erythrodiol SCHEMBL21183484 | 0.91 | PTPN1 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL30812366 | 0.91 | ALOX5 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL12422238 | 0.91 | ALOX5 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| Erythrodiol SCHEMBL18688666 | 0.91 | PTPN1 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL1011332 | 0.91 | ALOX5 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL5887832 | 0.91 | ALOX5 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 | |
| SCHEMBL1011334 | 0.91 | ALOX5 (1.00) | PTPN1ALOX5AKR1B10AKR1B1F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029414-B2 | Triterpenoid compounds and methods of use thereof | BIOTECHNOLOGY RESEARCH CORPORATION (HK) | 2015-05-12 | — | — | US | disclosed |
| US-9029414-B2 | Triterpenoid compounds and methods of use thereof | BIOTECHNOLOGY RESEARCH CORPORATION (HK) | 2015-05-12 | — | — | US | disclosed |