Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.48 |
| ▸ | PDE4A | P27815 | 1/20 | 0.48 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.48 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 6/20 | 0.44 |
| ▸ | CA2 | P00918 | 6/20 | 0.44 |
| ▸ | CA12 | O43570 | 5/20 | 0.43 |
| ▸ | CA9 | Q16790 | 5/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16705121 | 0.90 | PDE4B (0.57) | PDE4BPDE4APDE4CPDE4DCA1 | |
| SCHEMBL10172483 | 0.86 | AR (0.41) | PDE4BPDE4APDE4CPDE4DPGR | |
| SCHEMBL2280789 | 0.81 | CA1 (0.47) | CA1CA2CA12CA9CA4 | |
| SCHEMBL10172481 | 0.80 | AR (0.41) | PDE4BPDE4APDE4CPDE4DPGR | |
| SCHEMBL16705115 | 0.79 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DCA1 | |
| SCHEMBL16705119 | 0.79 | PDE4B (0.53) | PDE4BPDE4APDE4CPDE4DCA1 | |
| SCHEMBL596081 | 0.78 | CA1 (0.54) | CA1CA2CA12CA9CA4 | |
| SCHEMBL5528362 | 0.78 | CA1 (0.54) | CA1CA2CA12CA9CA4 | |
| SCHEMBL10217430 | 0.76 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DCA1 | |
| SCHEMBL2287109 | 0.76 | CA1 (0.44) | CA1CA2CA12CA9CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9029353-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2015-05-12 | — | — | US | disclosed |