Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 20/20 | 0.69 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HRH2 | P25021 | 1/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1486460 | 0.84 | TLR7 (0.88) | TLR7TLR8 | |
| SCHEMBL8572870 | 0.82 | TLR7 (0.74) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL1486429 | 0.82 | TLR7 (0.79) | TLR7TLR8NUDT1 | |
| SCHEMBL22559092 | 0.82 | TLR7 (1.00) | TLR7TLR8 | |
| SCHEMBL1486540 | 0.80 | TLR7 (0.55) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL4243750 | 0.80 | TLR7 (0.55) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL3353426 | 0.79 | TLR7 (0.52) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL5617708 | 0.79 | TLR7 (0.56) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL15911859 | 0.78 | TLR7 (0.70) | TLR7TLR8LMNAPOLBHRH2 | |
| SCHEMBL1486565 | 0.78 | TLR7 (0.46) | TLR7HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1673087-B1 | ALKOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2015-05-13 | — | — | EP | disclosed |