SCHEMBL4243750

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5617708	0.95	TLR7 (0.56)	TLR7TLR8LMNAPOLBHRH2
	SCHEMBL1486540	0.85	TLR7 (0.55)	TLR7TLR8LMNAPOLBHRH2
	SCHEMBL5617759	0.85	TLR7 (0.49)	TLR7TLR8
	SCHEMBL5617737	0.85	TLR7 (0.49)	TLR7TLR8
	SCHEMBL1486521	0.84	TLR7 (0.50)	TLR7TLR8LMNAPOLBHRH2
	SCHEMBL4240961	0.84	TLR7 (0.48)	TLR7TLR8LMNA
	SCHEMBL4064727	0.83	TLR7 (0.47)	TLR7TLR8ADORA2A
	SCHEMBL4243909	0.81	TLR7 (0.47)	TLR7TLR8
	SCHEMBL4239979	0.81	TLR7 (0.71)	TLR7TLR8
	SCHEMBL5617730	0.80	TLR7 (0.43)	TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.