SCHEMBL16705244

SCHEMBL16705244

CCCc1nc2c(N)nc3cc(O)ccc3c2n1CCCCNS(C)(=O)=O

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TLR7 Q9NYK1 17/20 0.65
TLR8 Q9NR97 7/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1486832 0.93 TLR7 (0.76) TLR7TLR8
SCHEMBL3864126 0.89 TLR7 (0.65) TLR7TLR8
SCHEMBL1486652 0.88 TLR7 (0.64) TLR7TLR8
SCHEMBL29852269 0.87 TLR7 (0.85) TLR7TLR8
SCHEMBL483689 0.87 TLR7 (0.85) TLR7TLR8
SCHEMBL4386167 0.86 TLR7 (0.61) TLR7TLR8
SCHEMBL1486696 0.85 TLR7 (0.76) TLR7TLR8
SCHEMBL4243584 0.83 TLR7 (0.46) TLR7TLR8
SCHEMBL4236222 0.83 TLR7 (0.58) TLR7TLR8
SCHEMBL4245885 0.83 TLR7 (0.55) TLR7TLR8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1673087-B1 ALKOXY SUBSTITUTED IMIDAZOQUINOLINES 3M INNOVATIVE PROPERTIES CO (US) 2015-05-13 EP disclosed