Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HPRT1 | P00492 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TK1 | P04183 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10047129 | 0.90 | TSHR (0.49) | TSHRKMT2AMEN1HPRT1KDM4E | |
| SCHEMBL10047093 | 0.81 | TSHR (0.42) | TSHRKMT2AMEN1HPRT1KDM4E | |
| SCHEMBL28942682 | 0.78 | TSHR (0.65) | TSHRKMT2AMEN1HPRT1KDM4E | |
| SCHEMBL21637053 | 0.77 | MEN1 (0.46) | TSHRKMT2AMEN1HPRT1TK1 | |
| SCHEMBL10076894 | 0.76 | HPRT1 (0.45) | TSHRKMT2AMEN1HPRT1KDM4E | |
| SCHEMBL16705270 | 0.75 | CDK1 (0.46) | TSHRHPRT1KDM4ENPC1RAB9A | |
| SCHEMBL12786366 | 0.75 | PNP (0.70) | TSHRKMT2AMEN1HPRT1LMNA | |
| SCHEMBL10047125 | 0.75 | MEN1 (0.46) | TSHRKMT2AMEN1HPRT1TK1 | |
| SCHEMBL14611764 | 0.73 | CDK1 (0.48) | TSHRHPRT1KDM4ENPC1RAB9A | |
| SCHEMBL5256051 | 0.72 | HPRT1 (0.65) | TSHRKMT2AMEN1HPRT1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2268607-B9 | PEPTIDE NUCLEIC ACID DERIVATIVES WITH GOOD CELL PENETRATION AND STRONG AFFINITY FOR NUCLEIC ACID | CTI BIO (KR) | 2015-05-13 | — | — | EP | disclosed |