Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.36 |
| ▸ | CCR8 | P51685 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALPL | P05186 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | ALPI | P09923 | 1/20 | 0.33 |
| ▸ | ALPG | P10696 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1755660 | 0.85 | — | — | |
| SCHEMBL29539234 | 0.85 | CCR1 (0.46) | CCR1CCR8GABRA1GABRG2GABRB3 | |
| SCHEMBL229994 | 0.85 | CCR1 (0.46) | CCR1CCR8GABRA1GABRG2GABRB3 | |
| SCHEMBL31354842 | 0.83 | CCR1 (0.46) | CCR1CCR8GABRA1GABRG2GABRB3 | |
| SCHEMBL700152 | 0.83 | CCR1 (0.46) | CCR1CCR8GABRA1GABRG2GABRB3 | |
| SCHEMBL19289237 | 0.74 | PARP1 (0.35) | CCR1CCR8GABRA1GABRG2GABRB3 | |
| SCHEMBL3419835 | 0.73 | CCR1 (0.73) | CCR1CCR8TGFBR1MAPK14RAB9A | |
| SCHEMBL16511928 | 0.73 | CYP3A4 (0.40) | CCR1CCR8GABRA1GABRG2GABRB3 | |
| SCHEMBL23598723 | 0.71 | MEN1 (0.70) | CCR1CCR8KDM4ELMNATP53 | |
| SCHEMBL10263463 | 0.71 | KDM4E (0.71) | CCR1CCR8KDM4ELMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1629063-B1 | ORGANIC ELECTROLUMINESCENT DEVICES AND METAL COMPLEX COMPOUNDS | UDC IRELAND LTD (IE) | 2015-05-13 | — | — | EP | disclosed |