SCHEMBL229994

SCHEMBL229994

Brc1cccc(-c2cccc(Br)n2)n1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR1 P32246 2/20 0.46
CCR8 P51685 2/20 0.46
KDM4E B2RXH2 1/20 0.42
LMNA P02545 1/20 0.42
TP53 P04637 1/20 0.42
ALPL P05186 1/20 0.42
HSP90AA1 P07900 1/20 0.42
ALPI P09923 1/20 0.42
ALPG P10696 1/20 0.42
ALOX15 P16050 1/20 0.42
MAPK1 P28482 1/20 0.42
HTT P42858 1/20 0.42
CCR5 P51681 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
L3MBTL1 Q9Y468 1/20 0.42
MEN1 O00255 1/20 0.39
RAB9A P51151 1/20 0.39
KMT2A Q03164 1/20 0.39
GABRA1 P14867 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29539234 1.00 CCR1 (0.46) CCR1CCR8KDM4ELMNATP53
SCHEMBL700152 0.97 CCR1 (0.46) CCR1CCR8KDM4ELMNATP53
SCHEMBL31354842 0.97 CCR1 (0.46) CCR1CCR8KDM4ELMNATP53
SCHEMBL16705267 0.85 CCR1 (0.36) CCR1CCR8KDM4ELMNATP53
SCHEMBL16511928 0.85 CYP3A4 (0.40) CCR1CCR8KDM4ELMNATP53
SCHEMBL3419835 0.85 CCR1 (0.73) CCR1CCR8RAB9ATGFBR1MAPK14
SCHEMBL23598723 0.83 MEN1 (0.70) CCR1CCR8KDM4ELMNATP53
SCHEMBL30485904 0.83 KDM4E (0.71) CCR1CCR8KDM4ELMNATP53
SCHEMBL29946428 0.83 KDM4E (0.71) CCR1CCR8KDM4ELMNATP53
SCHEMBL353379 0.83 KDM4E (0.71) CCR1CCR8KDM4ELMNATP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 203 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US claimed
EP-4473309-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2024-12-11 EP claimed
WO-2023196986-A1 PHOTOACTIVE ANTIBODY CONJUGATE Syncell (Taiwan) Inc. (TW) 2023-10-12 WO claimed
US-20230167144-A1 PREPARATION AND ITS APPLICATION OF A CYANIDE-BRIDGED METAL ORGANIC COMPOUND WITH INTRAMOLECULAR MAGNETIC TRANSFORMATION Hubei Jingmen Industrial Technology Research Institute Co., Ltd. (CN) 2023-06-01 US claimed
EP-1119573-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2001-08-01 EP claimed
WO-2000009512-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2000-02-24 WO claimed
CN-116917271-B Process for producing arylthiol ester compound AGC株式会社 2026-05-15 CN disclosed
US-20260125402-A1 Novel Carbonylation Catalysts And Methods Of Making The Same NOVOMER INC (US) 2026-05-07 US disclosed
US-20250362307-A1 PHOTOACTIVE ANTIBODY CONJUGATE LIAO JUNG CHI (TW) 2025-11-27 US disclosed
US-12459960-B2 Carbonylation catalysts and methods of making the same NOVOMER, INC. (US) 2025-11-04 US disclosed
EP-4631621-A2 NOVEL CARBONYLATION CATALYSTS AND METHODS OF MAKING THE SAME Novomer, Inc. (US) 2025-10-15 EP disclosed
EP-4319916-B1 NOVEL CARBONYLATION CATALYSTS AND METHODS OF MAKING THE SAME NOVOMER INC (US) 2025-08-27 EP disclosed
EP-4026881-B1 ORGANIC THIN FILM AND METHOD FOR PRODUCING ORGANIC THIN FILM JAPAN BROADCASTING CORP (JP) 2025-07-30 EP disclosed
EP-0787719-B1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN IND LTD (JP) 2001-08-16 EP disclosed
EP-1119573-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2001-08-01 EP disclosed
US-6177419-B1 ANTIOXIDANT CHELATE COMPOUNDS FOR PREVENTING OXYGEN FREE RADICAL-ASSOCIATED DISEASES IN MAMMALS; NEUROPROTECTANTS, SUPEROXIDE DISMUTASE (SOD), CATALASE (CAT) AND/OR PEROXIDASE (POD) MIMETICS EUKARION, INC. 2001-01-23 US disclosed
EP-1006135-A1 Conjugated N-fluoropyridinium salt-containing polymer and use of the same DAIKIN INDUSTRIES, LIMITED (JP) 2000-06-07 EP disclosed
WO-2000009512-A2 BIPYRIDINE MANGANESE COMPLEXES EUKARION, INC. (US) 2000-02-24 WO disclosed
US-5736274-A ANODE ACTIVE MATERIAL AND SOLID ELECTROLYTE FOR BATTERIES; HIGH ELECTROMOTIVE FORCE; HIGH ENERGY DENSITY; POLLUTION CONTROL; FLUORINATING AGENTS; LOW INTERNAL RESISTANCE IN CHARGING AND DISCHARGING DAIKIN INDUSTRIES, LTD. (JP) 1998-04-07 US disclosed
EP-0787719-A1 CONJUGATED N-FLUOROPYRIDINIUM SALT POLYMER AND USE THEREOF DAIKIN INDUSTRIES, LTD. (JP) 1997-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260125402-A1 Novel Carbonylation Catalysts And Methods Of Making The Same CBR1, CBR3, SOD1 CCR1 369/4885CCR8 1269/4885KDM4E 491/4885
US-12459960-B2 Carbonylation catalysts and methods of making the same CBR1, CBR3, DCXR CCR1 2138/4885CCR8 2408/4885KDM4E 923/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.