Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.42 |
| ▸ | PDE8B | O95263 | 1/20 | 0.37 |
| ▸ | OGA | O60502 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19850476 | 0.81 | GPR119 (0.47) | GPR119 | |
| SCHEMBL1118360 | 0.80 | GPR119 (0.56) | GPR119 | |
| SCHEMBL1118366 | 0.77 | GPR119 (0.71) | GPR119 | |
| SCHEMBL15133550 | 0.77 | CCNE1 (0.33) | — | |
| SCHEMBL14247134 | 0.75 | GPR119 (0.43) | GPR119PDE8BOGA | |
| SCHEMBL12036204 | 0.74 | GPR119 (0.61) | GPR119PDE8B | |
| SCHEMBL17029332 | 0.74 | NPC1 (0.31) | — | |
| SCHEMBL14247009 | 0.73 | GPR119 (0.46) | GPR119PDE8BOGA | |
| SCHEMBL12239174 | 0.73 | TSHR (0.50) | GPR119PDE8BOGA | |
| SCHEMBL2597089 | 0.71 | OGA (0.42) | GPR119PDE8BOGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2280704-B1 | OXYMETHYLENE ARYL COMPOUNDS AND USES THEREOF | CYMABAY THERAPEUTICS INC (US) | 2015-05-13 | — | — | EP | disclosed |