Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 18/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9887047 | 0.82 | BRD4 (0.49) | BRD4CYP1A2HSD17B10 | |
| SCHEMBL9886993 | 0.82 | CYP1A2 (0.46) | BRD4CYP1A2HSD17B10 | |
| SCHEMBL9974035 | 0.82 | BRD4 (0.42) | BRD4CYP1A2HSD17B10 | |
| SCHEMBL9932378 | 0.79 | BRD4 (0.56) | BRD4CYP1A2HSD17B10 | |
| SCHEMBL9974004 | 0.75 | BRD4 (0.42) | BRD4 | |
| SCHEMBL27725669 | 0.73 | CYP1A2 (0.62) | CYP1A2HSD17B10 | |
| SCHEMBL16694845 | 0.72 | BRD4 (0.43) | BRD4 | |
| SCHEMBL9282881 | 0.71 | BRD4 (0.41) | BRD4 | |
| SCHEMBL5064678 | 0.69 | ALDH1A1 (0.46) | CYP1A2HSD17B10 | |
| SCHEMBL16738316 | 0.68 | BRD4 (0.47) | BRD4CYP1A2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646446-B1 | BROMODOMAIN INHIBITORS AND USES THEREOF | CONSTELLATION PHARMACEUTICALS INC (US) | 2015-05-13 | — | — | EP | disclosed |