Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.61 |
| ▸ | RAB9A | P51151 | 3/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.61 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.61 |
| ▸ | HPGDS | O60760 | 1/20 | 0.61 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9973831 | 0.89 | MEN1 (0.67) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL14515854 | 0.88 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL16705449 | 0.86 | MMP1 (0.59) | MEN1KMT2AALDH1A1HPGDCYP3A4 | |
| SCHEMBL1589789 | 0.85 | MEN1 (0.83) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL1589795 | 0.85 | MEN1 (0.83) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9973830 | 0.83 | MEN1 (0.65) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL13712369 | 0.81 | MEN1 (0.79) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9973848 | 0.80 | KDM1A (0.67) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL35210122 | 0.80 | KDM1A (0.69) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD | |
| Pyrrolidine SCHEMBL10857316 | 0.79 | MEN1 (0.72) | MEN1KMT2ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1959915-B1 | MIXTURES COMPRISING ANTHRANILIC ACID AMIDES AND ANTIDANDRUFF AGENTS AS COSMETIC AND PHARMACEUTICAL COMPOSITIONS FOR ALLEVIATING ITCHING | SYMRISE AG (DE) | 2015-05-13 | — | — | EP | disclosed |