⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15604485 | 1.00 | — | — | |
| SCHEMBL9607208 | 0.80 | — | — | |
| SCHEMBL14213017 | 0.79 | — | — | |
| SCHEMBL16587788 | 0.77 | — | — | |
| SCHEMBL21113895 | 0.73 | — | — | |
| SCHEMBL15875677 | 0.73 | — | — | |
| SCHEMBL15875678 | 0.73 | — | — | |
| SCHEMBL15873305 | 0.73 | — | — | |
| SCHEMBL14213005 | 0.71 | SPHK1 (0.36) | — | |
| SCHEMBL16522617 | 0.71 | SPHK1 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9173883-B2 | Ring-substituted N-pyridinyl amides as kinase inhibitors | NOVARTIS AG (CH) | 2015-11-03 | — | — | US | disclosed |
| US-20150133473-A1 | NOVEL RING-SUBSTITUTED N-PYRIDINYL AMIDES AS KINASE INHIBITORS | NOVARTIS AG (CH) | 2015-05-14 | — | — | US | disclosed |