Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2154529 | 0.84 | HDAC1 (0.52) | HDAC1HDAC2KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL1310629 | 0.84 | HDAC1 (0.52) | HDAC1HDAC2KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL6015303 | 0.78 | HDAC1 (0.46) | HDAC1HDAC2ESR1KDM4E | |
| SCHEMBL20518465 | 0.78 | HDAC1 (0.46) | HDAC1HDAC2ESR1NFE2L2 | |
| SCHEMBL18707132 | 0.78 | HDAC1 (0.46) | HDAC1HDAC2ESR1NFE2L2 | |
| SCHEMBL6015299 | 0.78 | HDAC1 (0.46) | HDAC1HDAC2ESR1KDM4E | |
| SCHEMBL18734284 | 0.78 | HDAC1 (0.46) | HDAC1HDAC2ESR1NFE2L2 | |
| SCHEMBL3803230 | 0.76 | HDAC1 (0.52) | HDAC1HDAC2KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL2073331 | 0.76 | HDAC1 (0.52) | HDAC1HDAC2KDM4EKMT2ASMN1; SMN2 | |
| SCHEMBL14619953 | 0.76 | HDAC1 (0.52) | HDAC1HDAC2ESR1KDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150246097-A9 | Polyalkylene Polymer Compounds and Uses Thereof | BIOGEN IDEC MA INC. (US) | 2015-09-03 | — | — | US | disclosed |
| US-20150132259-A1 | Polyalkylene Polymer Compounds and Uses Thereof | BIOGEN IDEC MA INC. (US) | 2015-05-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150246097-A9 | Polyalkylene Polymer Compounds and Uses Thereof | HAVCR2, TLR3, CCR8 | HDAC1 1768/4885HDAC2 2121/4885ESR1 4754/4885 |
| US-20150132259-A1 | Polyalkylene Polymer Compounds and Uses Thereof | HAVCR2, TLR3, CCR8 | HDAC1 1768/4885HDAC2 2121/4885ESR1 4754/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.