Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 2/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 2/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670821 | 1.00 | ERN1 (0.33) | ERN1NPY2RALDH1A1ALOX15TSHR | |
| SCHEMBL1671187 | 0.78 | ERN1 (0.34) | ERN1MGLLESR1ESR2TTR | |
| SCHEMBL1671189 | 0.78 | ERN1 (0.34) | ERN1MGLLESR1ESR2TTR | |
| SCHEMBL19472004 | 0.70 | ERN1 (0.38) | ERN1NPY2RMAPK1MGLLESR1 | |
| SCHEMBL20913284 | 0.69 | ERN1 (0.41) | ERN1NPY2RMGLLESR1ESR2 | |
| SCHEMBL18529354 | 0.69 | ERN1 (0.41) | ERN1NPY2RMGLLESR1ESR2 | |
| SCHEMBL1682400 | 0.69 | ERN1 (0.41) | ERN1NPY2RMGLLESR1ESR2 | |
| SCHEMBL1670517 | 0.69 | KDM1A (0.33) | ERN1MGLLESR1ESR2TTR | |
| SCHEMBL1670320 | 0.69 | ESR1 (0.34) | ESR1ESR2TTR | |
| SCHEMBL1670615 | 0.69 | ESR1 (0.34) | ESR1ESR2TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |