⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19768736 | 0.85 | POLRMT (0.40) | — | |
| SCHEMBL16708514 | 0.85 | POLRMT (0.40) | — | |
| SCHEMBL16708568 | 0.79 | — | — | |
| SCHEMBL16708557 | 0.77 | POLRMT (0.35) | — | |
| SCHEMBL16708553 | 0.74 | POLRMT (0.35) | — | |
| SCHEMBL15259024 | 0.72 | STING1 (0.30) | — | |
| SCHEMBL16708600 | 0.72 | — | — | |
| SCHEMBL15257356 | 0.71 | — | — | |
| SCHEMBL23072069 | 0.70 | — | — | |
| SCHEMBL15257378 | 0.70 | CSNK1D (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9388208-B2 | Pyrrolo[1,2-f][1,2,4]triazines useful for treating respiratory syncitial virus infections | GILEAD SCIENCES, INC. (US) | 2016-07-12 | — | — | US | disclosed |
| US-20150133395-A1 | PYRROLO[1,2-f][1,2,4]TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | ROSEMOUNT INC. | 2015-05-14 | — | — | US | disclosed |