Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TTR | P02766 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1670948 | 1.00 | BRD4 (0.34) | BRD4ERN1GAAMAPK1TTR | |
| SCHEMBL1672952 | 0.86 | ESR2 (0.36) | GAAMAPK1 | |
| SCHEMBL1672953 | 0.86 | ESR2 (0.36) | GAAMAPK1 | |
| SCHEMBL1671187 | 0.86 | ERN1 (0.34) | ERN1TTR | |
| SCHEMBL1671189 | 0.86 | ERN1 (0.34) | ERN1TTR | |
| SCHEMBL1670649 | 0.84 | ESR1 (0.35) | TTR | |
| SCHEMBL1671281 | 0.81 | BRD4 (0.33) | BRD4ERN1 | |
| SCHEMBL1671278 | 0.81 | BRD4 (0.33) | BRD4ERN1 | |
| SCHEMBL1670273 | 0.78 | BRD4 (0.33) | BRD4ERN1TTR | |
| SCHEMBL1670272 | 0.78 | BRD4 (0.33) | BRD4ERN1TTR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011042477-A1 | SUBSTITUTED PYRROLES AND IMIDAZOLES AS ESTROGEN RECEPTOR LIGANDS | KARO BIO AB (SE) | 2011-04-14 | — | — | WO | claimed |