Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSPO | P30536 | 4/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.44 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 2/20 | 0.38 |
| ▸ | PPARA | Q07869 | 2/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409824 | 0.95 | TSPO (0.56) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL410648 | 0.85 | TSPO (0.56) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL19547481 | 0.84 | TSPO (0.58) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL18721926 | 0.83 | TSPO (0.57) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL410326 | 0.79 | TSPO (0.52) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL410544 | 0.78 | TSPO (0.78) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL19559321 | 0.77 | TSPO (0.50) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL19559315 | 0.76 | TSPO (0.62) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL19547504 | 0.75 | TSPO (0.56) | TSPOCYP1A2CYP2C19OPRM1DNM1 | |
| SCHEMBL408200 | 0.75 | TSPO (0.61) | TSPOCYP1A2CYP2C19OPRM1DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015070237-A1 | NEUROPROTECTIVE CHEMICALS AND METHODS FOR IDENTIFYING AND USING SAME | BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) | 2015-05-14 | — | — | WO | disclosed |