SCHEMBL16709796

SCHEMBL16709796

C=CC(=O)OCc1ccc(Sc2ccc3sccc3c2)cc1

nearest known ligand 0.40

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 2/20 0.40
MRGPRX4 Q96LA9 2/20 0.39
MEN1 O00255 1/20 0.37
KMT2A Q03164 1/20 0.37
CTNNB1 P35222 3/20 0.36
WNT3A P56704 3/20 0.36
PTPRC P08575 1/20 0.35
PTPN6 P29350 1/20 0.35
PTPN11 Q06124 1/20 0.35
PTPN22 Q9Y2R2 1/20 0.35
CA12 O43570 4/20 0.34
CA2 P00918 4/20 0.34
SIGMAR1 Q99720 1/20 0.34
TOP2A P11388 1/20 0.33
TOP2B Q02880 1/20 0.33
HCAR2 Q8TDS4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12268166 0.83 HCAR2 (0.43) MEN1KMT2ACA12TOP2ATOP2B
SCHEMBL16709779 0.80 THRB (0.42) MEN1KMT2ACA12TOP2ATOP2B
SCHEMBL16709762 0.79 HCAR2 (0.45) CA12TOP2ATOP2BHCAR2
SCHEMBL21577435 0.78 HCAR2 (0.50) KMT2ACA12TOP2ATOP2BHCAR2
SCHEMBL16709780 0.78 HCAR2 (0.50) KMT2ACA12TOP2ATOP2BHCAR2
SCHEMBL16709799 0.77 DHODH (0.40) PTPN22TOP2ATOP2BHCAR2
SCHEMBL16709763 0.76 KDM4E (0.40) MEN1KMT2ATOP2ATOP2BHCAR2
SCHEMBL16709802 0.76 HCAR2 (0.37) CA12TOP2ATOP2BHCAR2
SCHEMBL2556244 0.75 HCAR2 (0.50) MEN1KMT2ACA12HCAR2
SCHEMBL28270005 0.73 KDM4E (0.42) MEN1KMT2AHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2015068839-A1 POLYMERIZABLE COMPOUND, RESIN COMPOSITION USING SAME, CURED RESIN, AND OPTICAL MATERIAL 新日鉄住金化学株式会社 2015-05-14 WO disclosed