Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLRMT | O00411 | 1/20 | 0.82 |
| ▸ | P2RY2 | P41231 | 2/20 | 0.33 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.33 |
| ▸ | P2RY11 | Q96G91 | 1/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.30 |
| ▸ | P2RX2 | Q9UBL9 | 2/20 | 0.30 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.30 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.30 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16699057 | 0.98 | POLRMT (0.85) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16699054 | 0.98 | POLRMT (0.85) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL19779220 | 0.98 | POLRMT (0.85) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16698824 | 0.90 | POLRMT (1.00) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL19778887 | 0.90 | POLRMT (1.00) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16698822 | 0.90 | POLRMT (1.00) | POLRMTP2RY2P2RY1P2RY11P2RX3 | |
| SCHEMBL16708556 | 0.89 | POLRMT (0.70) | POLRMTP2RY2 | |
| SCHEMBL20960138 | 0.85 | POLRMT (0.65) | POLRMTP2RY2P2RY1P2RY11 | |
| SCHEMBL16698714 | 0.85 | POLRMT (0.65) | POLRMTP2RY2P2RY1P2RY11 | |
| SCHEMBL16698713 | 0.85 | POLRMT (0.65) | POLRMTP2RY2P2RY1P2RY11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015069939-A1 | PYRROLO [1,2,F] [1,2,4] TRIAZINES USEFUL FOR TREATING RESPIRATORY SYNCITIAL VIRUS INFECTIONS | GILEAD SCIENCES, INC. (US) | 2015-05-14 | — | — | WO | disclosed |