Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADK | P55263 | 1/20 | 0.31 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644948 | 0.89 | ADORA2A (0.41) | ADORA2AADKDOT1L | |
| SCHEMBL646988 | 0.79 | ADORA2A (0.41) | ADORA2A | |
| SCHEMBL13519772 | 0.79 | ADORA2A (0.41) | ADORA2A | |
| SCHEMBL648257 | 0.77 | ADORA2A (0.40) | ADORA2A | |
| SCHEMBL13519782 | 0.77 | ADORA2A (0.44) | ADORA2A | |
| SCHEMBL13531953 | 0.76 | ADORA2A (0.43) | ADORA2AADK | |
| SCHEMBL645160 | 0.75 | ADORA2A (0.43) | ADORA2A | |
| SCHEMBL646044 | 0.75 | ADORA2A (0.43) | ADORA2A | |
| SCHEMBL13531963 | 0.75 | ADORA2A (0.43) | ADORA2A | |
| SCHEMBL7598953 | 0.75 | ADORA2A (0.43) | ADORA2AADKDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2313102-A2 | BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | Biota Scientific Management (AU) | 2011-04-27 | — | — | EP | disclosed |
| WO-2010002877-A2 | BYCYCLIC NUCLEOSIDES AND NUCLEOTIDES AS THERAPEUTIC AGENTS | BIOTA SCIENTIFIC MANAGEMENT (AU) | 2010-01-07 | — | — | WO | disclosed |