Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 3/20 | 0.46 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | AOC3 | Q16853 | 2/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27526717 | 0.88 | TRPV1 (0.47) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL29177274 | 0.86 | UBE2T (0.51) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL28284732 | 0.84 | UBE2T (0.53) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL29177328 | 0.81 | UBE2T (0.49) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL28794004 | 0.79 | TRPV1 (0.49) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| SCHEMBL186136 | 0.79 | ALDH1A1 (0.46) | ALDH1A1MAPTLMNAHPGDPOLB | |
| SCHEMBL15152104 | 0.77 | HRH4 (0.46) | ALDH1A1MAPTALOX12HPGDPOLB | |
| SCHEMBL184999 | 0.77 | ALDH1A1 (0.47) | ALDH1A1MAPTLMNAHPGDPOLB | |
| SCHEMBL27837554 | 0.77 | UBE2T (0.50) | ALDH1A1MAPTLMNAALOX12NPSR1 | |
| Hydrochloric Acid SCHEMBL27676374 | 0.77 | KMT2A (0.49) | MAPTLMNAUBE2TPOLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1863766-B1 | CERTAIN SUBSTITUTED AMIDES, METHOD OF MAKING, AND METHOD OF USE THEREOF | GILEAD CONNECTICUT INC (US) | 2015-05-20 | — | — | EP | claimed |