Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233837 | 0.83 | MAP3K5 (0.63) | MAP3K5AKT1 | |
| SCHEMBL231489 | 0.75 | MAP3K5 (0.65) | MAP3K5AKT1 | |
| SCHEMBL231490 | 0.75 | MAP3K5 (0.65) | MAP3K5AKT1 | |
| SCHEMBL231864 | 0.74 | MAP3K5 (0.67) | MAP3K5AKT1 | |
| SCHEMBL231878 | 0.74 | MAP3K5 (0.68) | MAP3K5AKT1 | |
| SCHEMBL231879 | 0.74 | MAP3K5 (0.68) | MAP3K5AKT1 | |
| SCHEMBL16712435 | 0.72 | MAP3K5 (0.45) | MAP3K5AKT1 | |
| SCHEMBL232907 | 0.71 | MAP3K5 (0.64) | MAP3K5AKT1 | |
| SCHEMBL232728 | 0.71 | MAP3K5 (0.53) | MAP3K5AKT1 | |
| SCHEMBL235423 | 0.69 | MAP3K5 (0.48) | MAP3K5AKT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2588475-B1 | APOPTOSIS SIGNAL-REGULATING KINASE INHIBITORS | GILEAD SCIENCES INC (US) | 2015-05-20 | — | — | EP | disclosed |