Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD3 | O94806 | 5/20 | 0.77 |
| ▸ | PRKCG | P05129 | 5/20 | 0.77 |
| ▸ | PRKCB | P05771 | 5/20 | 0.77 |
| ▸ | PRKCA | P17252 | 5/20 | 0.77 |
| ▸ | PRKCH | P24723 | 5/20 | 0.77 |
| ▸ | PRKCI | P41743 | 5/20 | 0.77 |
| ▸ | PRKCE | Q02156 | 5/20 | 0.77 |
| ▸ | PRKCQ | Q04759 | 5/20 | 0.77 |
| ▸ | PRKCZ | Q05513 | 5/20 | 0.77 |
| ▸ | PRKCD | Q05655 | 5/20 | 0.77 |
| ▸ | PRKD1 | Q15139 | 5/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.77 |
| ▸ | PRKACA | P17612 | 4/20 | 0.77 |
| ▸ | PRKACG | P22612 | 4/20 | 0.77 |
| ▸ | PRKACB | P22694 | 4/20 | 0.77 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.77 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.77 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.77 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.77 |
| ▸ | ROCK2 | O75116 | 11/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29968762 | 0.87 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL1272907 | 0.87 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL30422637 | 0.87 | PRKD3 (1.00) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL5176161 | 0.86 | PRKD3 (0.97) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL30084459 | 0.86 | PRKD3 (0.97) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL29629288 | 0.86 | PRKD3 (0.97) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL29968274 | 0.86 | PRKD3 (0.97) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL1165381 | 0.86 | PRKD3 (0.97) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL7315948 | 0.86 | PRKD3 (0.74) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL31655516 | 0.85 | PRKD3 (0.95) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617214-B2 | Compounds for cognitive enhancement and methods of use thereof | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2017-04-11 | — | — | US | disclosed |
| US-9617214-B2 | Compounds for cognitive enhancement and methods of use thereof | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2017-04-11 | — | — | US | disclosed |
| US-20160272587-A1 | COMPOUNDS FOR COGNITIVE ENHANCEMENT AND METHODS OF USE THEREOF | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2016-09-22 | — | — | US | disclosed |
| US-20160272587-A1 | COMPOUNDS FOR COGNITIVE ENHANCEMENT AND METHODS OF USE THEREOF | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2016-09-22 | — | — | US | disclosed |
| WO-2015070170-A1 | COMPOUNDS FOR COGNITIVE ENHANCEMENT AND METHODS OF USE THEREOF | THE TRANSLATIONAL GENOMICS RESEARCH INSTITUTE (US) | 2015-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160272587-A1 | COMPOUNDS FOR COGNITIVE ENHANCEMENT AND METHODS OF USE THEREOF | ROCK1, ROCK2, RHOA | PRKD3 323/4885PRKCG 103/4885PRKCB 432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.