Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16731539 | 0.90 | PPARG (0.52) | PPARG | |
| SCHEMBL16731555 | 0.84 | PPARG (0.52) | PPARG | |
| SCHEMBL3457192 | 0.83 | NAMPT (0.53) | PPARG | |
| SCHEMBL15992143 | 0.83 | PPARG (0.57) | PPARG | |
| SCHEMBL27213518 | 0.83 | PPARG (0.61) | PPARG | |
| SCHEMBL16713356 | 0.83 | PPARG (0.59) | PPARG | |
| SCHEMBL16713326 | 0.82 | PPARG (0.56) | PPARG | |
| SCHEMBL16713358 | 0.81 | PPARG (0.57) | PPARG | |
| SCHEMBL16713357 | 0.81 | PPARG (0.57) | PPARG | |
| SCHEMBL16713334 | 0.80 | PPARG (0.55) | PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9309227-B2 | N-biphenylmethylbenzimidazole modulators of PPARG | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-12 | — | — | US | disclosed |
| US-9309227-B2 | N-biphenylmethylbenzimidazole modulators of PPARG | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-12 | — | — | US | disclosed |
| US-9309227-B2 | N-biphenylmethylbenzimidazole modulators of PPARG | THE SCRIPPS RESEARCH INSTITUTE (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150141464-A1 | N-BIPHENYLMETHYLBENZIMIDAZOLE MODULATORS OF PPARG | SCRIPPS RESEARCH INSTITUTE, THE | 2015-05-21 | — | — | US | disclosed |
| US-20150141464-A1 | N-BIPHENYLMETHYLBENZIMIDAZOLE MODULATORS OF PPARG | SCRIPPS RESEARCH INSTITUTE, THE | 2015-05-21 | — | — | US | disclosed |
| US-20150141464-A1 | N-BIPHENYLMETHYLBENZIMIDAZOLE MODULATORS OF PPARG | SCRIPPS RESEARCH INSTITUTE, THE | 2015-05-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150141464-A1 | N-BIPHENYLMETHYLBENZIMIDAZOLE MODULATORS OF PPARG | CDK5, PPARG, CDK5R1 | PPARG 2/4885HTR4 474/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.